Race and Ethnicity
Rates of breast cancer in the U.S. vary by race and ethnicity.
Non-Hispanic white women and non-Hispanic Black women have the highest incidence of breast cancer (rate of new breast cancer cases) overall [664]. Hispanic women have the lowest incidence (see Figure 2.3 below) [664].
Figure 2.3
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Source: 2015-2019 SEER data, 2022 [664] |
Learn about differences in breast cancer rates in the U.S. and around the world.
Lifetime risk of breast cancer by race and ethnicity
The lifetime risk of breast cancer for women in the U.S. is about 13 percent [659]. However, this risk varies by race and ethnic group.
Race and ethnicity |
Lifetime risk of breast cancer |
Non-Hispanic White |
14% |
Non-Hispanic Black |
12% |
Non-Hispanic Asian and Pacific Islander |
12% |
Hispanic |
11% |
Non-Hispanic American Indian and Alaska Native |
10% |
Source: 2017-2019 SEER data, 2022 [665] |
Why are there differences in breast cancer rates?
One reason behind differences in breast cancer rates may be that the prevalence of some risk factors for breast cancer vary by race and ethnic group [9]. This means some risk factors are more common in women of some racial and ethnic groups than in other women.
Known risk factors that vary by race and ethnicity include [340-349]:
- Age at first period
- Age at menopause
- Age at first childbirth
- Body weight
- Breastfeeding
- Number of childbirths
- Menopausal hormone therapy (postmenopausal hormone use, hormone replacement therapy (HRT))
For example, white women are more likely than women of some other ethnicities (including Black and Hispanic women) to have children at a later age, to have fewer children and to use menopausal hormone therapy [9,342-343,347,349]. These factors are linked to an increased breast cancer risk [9].
Learn more about rates of breast cancer by race and ethnicity.
Black women
Overall, Black women have a slightly lower rate of breast cancer compared to white women [664].
However, there are differences by age [666]:
- Among younger women, Black and non-Hispanic Black women have higher rates of breast cancer compared to white and non-Hispanic white women.
- Among older women, white and non-Hispanic white women have higher rates of breast cancer compared to Black and non-Hispanic Black women.
For example, in 2019 (most recent data available), among women ages 15-39, the incidence of breast cancer in Black women was 28 per 100,000 women and the incidence of breast cancer in white women was 23 per 100,000 women [667].
The reasons behind these differences are under study. These may include some risk factors that are more common in women of some racial and ethnic groups than in other women as well as differences in tumor biology [340-349].
Age at diagnosis
Black women tend to be diagnosed with breast cancer at a younger age than white women [5].
From 2014-2018 (most recent data available), the median age at breast cancer diagnosis for Black women was 60, compared to 64 for white women [5].
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Triple negative breast cancer (TNBC)
Incidence rates (new cases per year) of triple negative breast cancer (TNBC) differ by race and ethnicity.
TNBC is:
- Estrogen receptor-negative (ER-negative)
- Progesterone receptor-negative (PR-negative)
- HER2-negative
TNBC is more common among Black and African American women than among women of other ethnicities [346,351-354]. TNBC may also be more common among Hispanic women compared to white and non-Hispanic white women [355-357].
TNBC is often aggressive. TNBC is more likely than estrogen receptor-positive (ER-positive) breast cancers to recur, at least within the first 5 years after diagnosis [346,358-360].
Possible reasons for differences in rates of TNBC
Although the reasons for racial and ethnic differences in rates of TNBC aren’t clear, some lifestyle factors may play a role [361].
Compared to white and non-Hispanic white women, Black and African American women tend to [125-126,343,361-363]:
- Have lower rates of breastfeeding
- Carry excess weight in the abdomen area
Both of these factors may be linked to an increased risk of TNBC [125-126,343,361-363].
Women with certain reproductive and lifestyle factors may have a lower risk of ER-positive breast cancers, but not a lower risk of ER-negative breast cancers, including TNBC [74-75,125,343,349,362].
Black and African American women may be more likely than white women to have protective factors that may not be linked to the risk of TNBC as much as they are linked to the risk of ER-positive cancers [74-75,79,125,343,349,362].
For example, Black and African American women are more likely than white and non-Hispanic white women to [125,343,349,362-365]:
- Have more children
- Be a younger age at first childbirth
- Be overweight or obese before menopause
Although these factors are linked to a lower risk of breast cancer, this lower risk may be limited to ER-positive breast cancers [74-75,79,125,343,349,362]. There’s even some evidence these factors may be linked to an increased risk of TNBC [74-75,79,125,343,362].
These topics are under study.
Learn more about the molecular subtypes of breast cancer.
Learn more about rates of breast cancer by race and ethnicity.
Updated 07/21/22